Best Practice Case Studies-Bone Lesions: Benign and Malignant

Pdf Summary

The article "Bone Lesions: Benign and Malignant" by Rani Gereige and Mudra Kumar, published in Pediatrics in Review, provides an overview of benign and malignant bone tumors in children and adolescents. It discusses their clinical presentation, diagnosis, and management strategies.<br /><br />Bone lesions can be classified into benign, malignant, and non-neoplastic categories. Benign lesions, such as osteochondromas and fibromas, are more common than malignant ones. However, malignant bone tumors like osteosarcoma and Ewing sarcoma are significant in pediatric oncology. Osteosarcoma, the most common malignant bone tumor, typically presents with localized pain and swelling, often around the knee. Ewing sarcoma usually involves pain, a palpable mass, and may metastasize to the lungs or bones. Both tumors require a comprehensive approach for diagnosis and management, often involving imaging, biopsy, and a multidisciplinary treatment team.<br /><br />Diagnosis begins with a plain radiograph, which can often differentiate between benign and malignant lesions. Malignant tumors generally show ill-defined margins and require further imaging like MRI or CT to assess tumor extent and plan surgical interventions. Biopsy is crucial and should be performed at specialized centers to ensure accurate diagnosis and appropriate treatment.<br /><br />Management of malignant bone tumors includes chemotherapy, radiotherapy, and possibly surgery, with a focus on limb salvage when feasible. Benign lesions usually require conservative management but may need surgical intervention if they cause functional impairment or have premalignant features.<br /><br />The article emphasizes that pediatricians should maintain a high suspicion for bone tumors when children present with bone pain or incidental lesions on radiographs, ensuring timely referral to specialists for further evaluation and management.

Meta Tag

Edition 3rd Edition

Related Case 3rd Edition, CASE 41

Topic Oncology

Keywords

3rd Edition, CASE 41

3rd Edition

Oncology

bone lesions

benign tumors

malignant tumors

osteosarcoma

Ewing sarcoma

pediatric oncology

diagnosis

management strategies

radiograph

multidisciplinary treatment